Organonitrogen Compounds
Medchemexpress LLC Metformin (hydrochloride) | 1115-70-4 | 100.0% | 165.62 | 500 MG
Metformin (hydrochloride) | 1115-70-4 | 100.0% | 165.62 | 500 MG
Apexbio Technology LLC Metformin HCl, 50g. Cas: 1115-70-4 MFCD: MFCD00012582. Anti-diabetic drug
Metformin, a widely used anti-diabetic drug has potential efficacy as an anti-cancer drug. Metformin inhibits the proliferation of a range of cancer cells including prostate, colon, breast, ovarian, and glioma lines. 1115-70-4. MFCD00012582
Medchemexpress LLC PSB-1115 | 152529-79-8 | 99.0% | 350.35 g·mol⁻¹ | C14H14N4O5S | 100 MG
PSB-1115 is a selective A2B adenosine receptor antagonist used as a research tool to block A2B-mediated signaling in vitro and in vivo. It is reported to antagonize adenosine-mediated effects in animal models and to inhibit TNBS-induced responses.
- Selective A2B adenosine receptor antagonist for research use.
- High purity (99.0%) solid suitable for biological assays.
- Chemical formula C14H14N4O5S; molecular weight 350.35 g·mol⁻¹.
- Soluble in DMSO (100 mg/mL) and water (10 mg/mL) with sonication or warming.
- Recommended storage at -20°C; in solution, store at -80°C for long-term stability.
- Reported in vivo activity at 0.5 mg/kg (i.p.) in mouse mucociliary clearance studies.
Medchemexpress LLC Imidodicarbonimidic diamide, N-phenyl-, hydrochloride | 55-57-2 | 99.8% | 213.67 | C8H12ClN5 | 25 G
Phenylbiguanide hydrochloride is the hydrochloride salt of phenylbiguanide, a selective 5-HT3 receptor agonist commonly used in receptor pharmacology and in vitro pharmacological assays. It is supplied as a research-grade reagent with supporting documentation for characterization and safe handling.
- Selective 5-HT3 receptor agonist (EC50 ≈ 3.0 μM).
- High purity: 99.8% by analytical testing.
- Molecular weight: 213.67 g/mol.
- CAS number: 55-57-2.
- Available in multiple pack sizes, including 25 g.
- Provided with datasheet and safety data sheet for handling and storage.
Apexbio Technology LLC PSB 1115 152529-79-8 10mg
PSB 1115 is a selective antagonist targeting the human A2B adenosine receptor It is designed to inhibit receptor-mediated signaling pathways associated with adenosine receptors thereby regulating processes related to inflammation and immune response PSB 1115 exerts its biological activity primarily through antagonism of the A2B adenosine receptor In experimental studies PSB 1115 demonstrates inhibition of acetylcholine-induced contractions triggered by 2 4 6-trinitrobenzene sulfonic acid (TNBS) a commonly used method in gastrointestinal inflammation research Based on these pharmacological properties PSB 1115 holds research potential in investigating inflammatory response immune regulation and mechanisms underlying inflammation-related disorders
Apexbio Technology LLC Metformin HCl 1115-70-4 10g
Metformin hydrochloride (Metformin HCl CAS 1115-70-4) is a widely studied small molecule employed in biomedical research primarily for investigating glucose metabolism and type 2 diabetes mechanisms It acts through selective inhibition of hepatic gluconeogenesis without directly increasing insulin secretion The molecular targets include activation of AMP-activated protein kinase (AMPK) subsequently suppressing acetyl-CoA carboxylase (ACC) activity attenuating lipid biosynthesis and promoting fatty acid oxidation Additionally metformin inhibits mitochondrial glycerophosphate dehydrogenase (mGPD) changing cellular redox status and reducing lactate-driven gluconeogenesis pathways Key research applications of Metformin HCl include studies on glucose homeostasis metabolic disorders and AMPK signaling cascades
Medchemexpress LLC Biguanide | 56-03-1 | 98.1% | 100 MG
Biguanide is an orally active antihyperglycemic research reagent used to investigate mitochondrial metabolism and insulin signaling. It inhibits mitochondrial ATP production and activates the LKB1-AMPK pathway, altering cellular energy homeostasis.
- Used to study mitochondrial metabolism and AMPK signaling.
- Inhibits mitochondrial ATP production.
- Enhances insulin-receptor activation and downstream signaling.
- Typical purity 98.1% for research use.
- Provided as a solid suitable for in vitro and in vivo model studies.
Medchemexpress LLC Biguanide | 56-03-1 | 98.1% | 25 MG
Biguanide is a small-molecule antihyperglycemic research reagent (CAS 56-03-1) that inhibits mitochondrial ATP production, activates the LKB1-AMPK signaling pathway, and enhances insulin-receptor signaling. It is intended for research use only.
- Antihyperglycemic activity; modulates mitochondrial metabolism.
- Activates LKB1-AMPK signaling and enhances insulin receptor signaling.
- Molecular formula C2H7N5; molecular weight 101.11 g/mol.
- Supplied as a solid in small pack sizes for research applications.
- For research use only; not for human therapeutic use.
Medchemexpress LLC PSB-1115 | 152529-79-8 | 99.0% | 350.35 | C14H14N4O5S | 5 MG
PSB-1115 is a selective A2B adenosine receptor antagonist supplied for research use to investigate A2B-mediated signaling and physiological responses. It has documented activity in TNBS-induced contraction models and is provided in solid and solution formats for experimental applications.
- Selective A2B adenosine receptor antagonist.
- Research-use compound for A2B receptor studies.
- Purity 99.0%.
- Molecular formula C14H14N4O5S; molecular weight 350.35.
- CAS number 152529-79-8.
- Available in solid 5 mg and solution 10 mM 1 mL in DMSO.
- Store at -20°C; protect from light. In solvent: -80°C for 6 months, -20°C for 1 month.
Sigma Aldrich Fine Chemicals Biosciences Metformin hydrochloride | 1115-70-4 | MFCD00012582 | 200 mg
Metformin hydrochloride | Mol Wt: 165.62 | 1115-70-4 | MFCD00012582 | 200 mg
eMolecules 2-Dimethylaminopyridine | 5683-33-0 | MFCD00006261 | 25g
Combi-Blocks, Inc. | 2-Dimethylaminopyridine | 25g | 586077927 | QD-8088 | 95.000 | 5683-33-0 | MFCD00006261 | 122.171 | C7H10N2
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Medchemexpress LLC Phosphoenolpyruvic acid potassium (Standard) | 99.0% | 100 MG
Phosphoenolpyruvic acid potassium (Standard) | 99.0% | 100 MG
eMolecules Methyl 3-amino-4-(cyclohexylamino)benzoate | 503859-27-6 | MFCD13343558 | 1g
Combi-Blocks | Methyl 3-amino-4-(cyclohexylamino)benzoate | 1g | 205414545 | WZ-9028 | 98.000 | 503859-27-6 | MFCD13343558 | 248.326 | C14H20N2O2
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